Onsior®

Relieve pain just where it’s needed with Onsior® tablets for cats, Onsior® tablets for dogs and Onsior® Solution for injection.

Onsior® is the only pain relief that has proven tissue selectivity^7,8 and COX-2 selectivity.^13,14 And, is available in a range of convenient, and easy to dose formulations.

Species:

Dogs, Cats

ONSIOR® INJECTABLE- Indications:

Onsior® Solution for Injection delivers 24 hours of relief from pain, and inflammation

Dogs:

Provides relief of pain, and inflammation associated with orthopedic or soft tissue surgery.

Cats:

As an adjunctive medication in the control of postoperative pain, and inflammation associated with onychectomy, ovariohysterectomy, and castration in cats.

Key features:

Tissue selectivity; high COX-2 selectivity; short blood half life; rapid Tmax.

Key benefits:

Safe and effective; relieves pain where it’s needed; no loading dose required.

ONSIOR® TABLETS- Indications:

Onsior® is different from other NSAIDs. It’s both tissue-selective,² and COX-2 selective^3,4 for dogs, and cats providing relief right where it’s needed.

Dogs:

For the relief of pain, and inflammation associated with osteoarthritis.

Cats:

1. Relief of acute pain, and inflammation associated with cat bites, and scratches with, and without abscesses, and musculoskeletal injuries such as sprains, and strains in cats
2. As an adjunctive medication, in the control of postoperative pain, and inflammation associated with onychectomy, ovariohysterectomy, and castration in cats.

   Key features:

   Tissue selectivity; high COX-2 selectivity; short blood half life; rapid Tmax.

   Key benefits:

   Safe and effective; relieves pain where it’s needed; once daily administration; highly palatable; easy to administer.

Important Safety Information:

The label contains complete use information, including cautions, and warnings. Always read, understand and follow the label, and use directions.

¹Giraudel JM et al. Evaluation of orally administered robenacoxib versus ketoprofen for treatment of acute pain and inflammation associated with musculoskeletal disorders in cats. Am J Vet Res. 2010;71:710-19.
²Canadian Metacam® Oral Suspension for Cats product insert.
³Reymond, N, Speranza C, Gruet P, et al. Robenacoxib vs carprofen for the treatment of canine osteoarthritis; a randomized, noninferiority clinical trial. J Vet Pharmacal Ther. 35 (2):175-83.
⁴NAH Internal Study - NAH CRA09-79-Sept 2009.
⁷Pelligand L et al. Pharmacokinetic and pharmacodynamic modelling of robenacoxib in a feline tissue cage model of inflammation. J Vet Pharmacol Ther. 2012;35(1):19-32.
⁸Silber HE, Burgener C, Letellier IM, et al. Population pharmacokinetic analysis of blood and joint synovial fluid concentrations of robenacoxib from healthy dogs and dogs with osteoarthritis. Pharm Res. 2010 Dec;27(12):2633-45.
¹³Giraudel JM, Toutain PL, King JN, Lees P. Differential inhibition of cyclooxygenase isoenzymes in the cat by the NSAID robenacoxib. J Vet Pharmacol Ther. 2009, Feb;32(1):31-40.
¹⁴King JN, Rudaz C, Borer L, Jung M, Seewald W, Lees P. In vitro and ex vivo inhibition of canine cyclooxygenase isoforms by robenacoxib: a comparative study. Res Vet Sci, 2010 Jun;88(3):497-506.